How to оpen PDF in Adobe Reader instead in IE

Sometimes PDF files are been opened in Internet Explorer while we want them open in Adobe Reader. 

1. Make Adobe Reader default.

2. Disable IE integration.

3. IE - General - "Open pop-ups in a new windows".

4. Add a site to local trusted sites.

I managed to work at Metropolinet, while I got this knowledge (thanks to Kseniya).